发汗除湿方治疗类风湿性关节炎的疗效分析

Curative effect of diaphoresis-inducing and dampness-removing prescription for rheumatoid arthritis

目的观察发汗除湿方治疗类风湿关节炎的临床疗效。方法选择诊断明确的120例类风湿关节炎患者,随机分为对照组57例、治疗组63例,均给予甲氨蝶呤口服,治疗组加用发汗方,对照组加用尼美舒利,分别在治疗前及治疗后30d、治疗后90d进行28个关节疾病活动评分(DAS28)。结果治疗30d、90d后,治疗组总有效率分别为71.7%、88.3%,对照组总有效率分别为49.1%、73.6%。两组总有效率差异有统计学意义(P<0.05)。结论发汗除湿方联合甲氨蝶呤治疗类风湿性关节炎疗效明确可靠。

Objective To observe the therapeutic effect of diaphoresis-inducing and dampness-removing prescription on rheumatoid arthritis（RA）.Methods One hundred and twenty patients with established RA were randomly divided into control group（n=57） and treatment group（n=63）.Patients in control group were treated with oral methotrexate（MTX） plus nimesulide and those in treatment were treated with MTX plus diaphoresis-inducing and dampness-removing prescription.Disease activity in 28 joints was scored 30 days before treatment,and 30 and 90 days after treatment.Results The total effective rates were significantly higher for treatment group 30 and 90 days after treatment than for control group 30 days after treatment（71.7% and 88.3% vs 49.1% and 73.6%,P0.05）.Conclusion Combined diaphoresis-inducing and dampness-removing prescription and MTX is a reliable effective therapy for RA.