慢性淋巴细胞白血病研究最新进展：第53届美国血液学会年会报道

Report on recent progress of chronic lymphocytic leukemia in the 53rd annual meeting of American Society of Hematology

慢性淋巴细胞白血病（CLL）是一种以B淋巴细胞在血液、骨髓、淋巴结或脾脏组织中克隆性增殖为特点的恶性血液疾病，在西方国家中发病率较高。但目前随着各项检查手段的发展，中国CLL的患者也呈现增多趋势。过去的数十年中，在CLL的发病机制、疾病诊断及治疗方面的各项研究均有了很大的进展。第53届美国血液学会（ASH）年会报告了大量关于CLL发病机制、诊断及预后、治疗等方面的最新进展，使人们对CLL疾病的发生发展过程有了更深入的了解，并且可以为临床医生更好地治疗患者起到一定指导作用。

Chronic lymphocytic leukemia （CLL）, the most frequent form of leukemia in Western countries, is characterized by the elonal proliferation and accumulation of neoplastic B lymphocytes in the blood, bone marrow, lymph nodes and spleen. During the past decades, important advances have been made in the understanding of the biology, pathology, diagnosis and treatment of CLL. In the 53rd ASH annual meeting, lots of new discoveries about the biology, prognosis, and treatment of CLL were introduced which lead us to further understand CLL and may provide more or better treatments for CLL patients.