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综合疗法治疗中晚期直肠癌26例 被引量:3

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摘要 目的分析中晚期直肠癌综合治疗方法、临床疗效及预后。方法对26例中晚期直肠癌患者进行治疗,其中19例采取术前放化疗同步新辅助治疗+手术切除癌灶+术后辅助化疗和(或)切除转移灶和(或)射频治疗,7例肠梗阻及出血病例,先行造口术解除或减轻梗阻、出血,再行放化疗。结果术前放化疗效果好,肿瘤降期或降级23例,占88.46%,1例死于术后心功能不全。26例患者出现不同程度骨髓抑制及胃肠道反应,1例出现放射性肠炎,1例出现小肠粘连梗阻,行手术切除病变肠段,2例出现吻合121瘘,4例出现切1:3延迟愈合。出院后随访6-24个月,其中2例死于恶性肿瘤进展。结论术前放化疗能使肿瘤降期或降级,综合治疗可能延长中晚期直肠癌患者的生存期,是较为理想的治疗模式。但同时应注意预防及控制放化疗毒副作用。
出处 《肿瘤研究与临床》 CAS 2012年第1期54-55,共2页 Cancer Research and Clinic
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