摘要
血浆D-二聚体是纤溶酶水解交联纤维蛋白形成的降解产物之一,为继发性纤溶特有的代谢物,其含量变化可作为体内高凝状态和原发性与继发性纤溶鉴别的可靠指标,也可作为溶栓治疗有效性的观察指标。近年来,D-二聚体检测在临床得到新的应用,尤其对心房颤动患者血栓的诊断。现就血浆D-二聚体检测及其对心房颤动患者血栓诊断的研究进展予以综述。
Plasma D-dimer is one of the degradation products of the cross-linked fibrin hydrolyzed by fibrinolysin and is also a unique metabolite of secondary fibrolysis. The change of its content is a reliable indicator for the identification of the hypercoagulabale state in vivo and primary and secondary fibrinolysis, as well as for the observation of the effectiveness of thrombolytic therapy. In recent years, D-dimer determination has new clinical applications, especially in diagnosis of thrombi in atrial fibrillation. Here is to make a review on the research progress of D-dimer detection and its diagnosis value for thrombus in atrial fibrillation patients.
出处
《医学综述》
2012年第5期726-729,共4页
Medical Recapitulate
