伊曲康唑治疗40例肺结核合并真菌感染的临床分析

Clinical analysis of itraconazole treatment for 40 cases of fungal infection in pulmonary tuberculosis

目的评价伊曲康唑治疗肺结核合并真菌感染的临床疗效和安全性。方法回顾性分析40例肺结核合并真菌感染患者在抗结核治疗同时,应用伊曲康唑治疗42d的临床疗效和不良反应。结果 40例患者中,治愈15例,有效21例,有效率为90.0%,真菌清除率为87.5%,不良反应发生率为7.5%。结论伊曲康唑具有较好的临床疗效及安全性,可用于肺结核患者真菌感染的治疗。

Objective To evaluate the clinical efficacy and safety of itraconazole treatment for fungal infection in pulmonary tuberculosis.Methods Retrospective study was employed to analyze the clinical efficacy and adverse response of 42 days of itraconazole treatment for 40 patients with pulmonary tuberculosis combined fungal infections who accepted anti-tuberculosis treatment at the same time.Results Among 40 patients,15 patients were cured,21 patients showed that the treatment was effective,with the effective rate of 90.5% and the fungal clearance rate of 87.5%.The incidence rate of adverse response was 7.5%.Conclusion Itraconazole has good clinical efficacy and safety,and can be used for treatment of fungal infection in patients with pulmonary tuberculosis.