摘要
趋化因子受体CXCR4是HIV进入宿主细胞的辅助受体之一,在HIV进入免疫细胞过程中起着重要作用。以CXCR4为靶点的新型抗HIV药物的设计与开发已成为抗艾滋病研究领域的一个热点课题。综述了CXCR4抑制剂在抗HIV治疗领域中的研究进展。
Chemokine receptor CXCR4 is one of major coreceptors for HIV-1 entering into host cells, and it plays an important role in this process. The design and development of a novel anti-HIV drag targeting CXCR4 has become a hot topic in the AIDS field. This paper provides an overview of the drag discovery in the field of anti-HIV treatment targeting CXCR4 receptor.
出处
《重庆理工大学学报(自然科学)》
CAS
2012年第2期40-46,70,共8页
Journal of Chongqing University of Technology:Natural Science