静脉导管感染病原菌的变迁和耐药性分析

Changes and resistance analysis of pathogens from venous catheter

目的了解静脉导管留置感染病原菌的分布及耐药情况。方法对该院2008年1月至2011年8月静脉导管尖端培养所分离的67株病原菌及其耐药性进行回顾性分析。结果分离出革兰阳性球菌占38.80%,革兰阴性菌占40.30%,真菌占20.90%,最常见的3种感染菌分别为凝固酶阴性葡萄球菌(26.87%)、鲍曼不动杆菌(16.42%)、铜绿假单胞菌(10.45%);耐甲氧西林凝固酶阴性葡萄球菌(MRSCN)和耐甲氧西林金黄色葡萄球菌(MRSA)的检出率均为83.33%,感染菌呈多重耐药。结论非发酵菌和凝固酶阴性葡萄球菌是静脉导管留置感染的最常见病原菌,检出病原菌对常用抗生素耐药性较高。

Objective To understand the distribution and drug resistance of bacteria on the venous duct. Methods The distribution of 67 pathogenic bacteria isolated from venous duct and the drug resistance of bacteria from January 2008 to August 2011 were retrospectively analyzed. Results Strains of pathogens were isolated from venous duct,of which gram-positive cocci was 38.80% ,gram-negative bacteria was 40. 30% ,and yeast was 20. 90%. The 3 most common bacteria were isolated, of which the coagulase negative staphylococci（CNS）was accounted for 26. 87 %, acinetobacter baumannii was 16.42 e//00 ,and pseudomonas aeruginosa was 10.45 %. Methieillin-resistant S. aureus and Methicillin-resistant S. coagulase-negative were accounted for 83. 33%. The pathogens were multidrug resistance. Conclusion Non-zymophyte and S. coagulase-negative are the major pathogenic bacteria and they had relatively high antibiotic resistance commonly against antibiotics.