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宫颈癌组织中Has-miRNA-199a-5p的表达变化 被引量:2

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摘要 目的观察宫颈癌组织中has-miRNA-199a-5p的表达变化。方法采用茎环RT-PCR法检测50例宫颈癌组织(观察组)和50例非癌疾病切除的正常宫颈组织(对照组)中has-miRNA-199a-5p。结果观察组has-miR-NA-199a-5p表达量为38.62±16.57,对照组为5.46±4.89,P<0.01。高分化宫颈癌组织has-miRNA-199a-5p表达量为5.67±4.35,中低分化宫颈癌组织为40.28±17.13,P<0.01。结论宫颈癌组织has-miRNA-199a-5p异常高表达,且表达量与宫颈癌分化程度有关。
出处 《山东医药》 CAS 2012年第6期40-42,共3页 Shandong Medical Journal
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