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pH敏感性药物释放机制的研究进展

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摘要 目的:介绍pH敏感性药物在不同释药系统中的释放机制。方法:根据国内外文献报道结果,进行分析、归纳、总结,并对其发展趋势作了展望。结果:从pH敏感性药物在脉冲式释药系统、自调式释药系统、pH敏感性结肠定位释药系统、pH敏感性微囊膜等系统的释放机制、影响药物释放的因素及其应用等方面作了综述。结论:pH敏感性药物具有广阔的应用前景,其释放机制因给药系统而异,值得深入研究。
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2012年第5期375-378,共4页 Chinese Journal of Hospital Pharmacy
基金 甘肃省科技支撑计划项目(编号:0708NKCA129) 兰州大学第二医院医学研究基金(编号:YJ2010-08)
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