摘要
在无溶剂条件下,芳香醛与5,5-二甲基-1,3-环己二酮或1,3-环己二酮经氨基磺酸锂催化缩合反应合成了氧杂蒽.结果表明,当催化剂用量为3%(摩尔分数)时,在120℃反应40~70 min,产率高达90%以上.此外,探讨了该反应的氨基磺酸锂催化机理.该合成方法具有操作简单、反应时间短、产率高及对环境友好等优点,是现有氧杂蒽化合物合成方法的一个重要补充.
An efficient synthesis of 9-aryl-1,2,3,4,5,6,7,8-octahydroxanthene-1,8-dione via condensation of aromatic aldehydes with 5,5-dimethyl-1,3-cyclohexanedione or cyclohexane-1,3-dione using LiNH2SO3 as an eco-friendly catalyst under solvent-free condition was described.The results indicate that the yields is up to 90% when using 3%(molar fraction) LiNH2SO3 and reacting at 120 ℃ for 40—70 min.Furthermore,a proposed reaction mechanism for the reaction catalyzed by LiNH2SO3 was speculated.The present methodology offers several advantages such as excellent yields,simple procedure,short reaction time and mild conditions making it an important supplement to the existing methods.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2012年第3期507-510,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金(批准号:21162025
20862016
20662009)
乌鲁木齐市科技计划项目(批准号:H101133001)资助
关键词
氨基磺酸锂
无溶剂
芳香醛
1
3-环己二酮
氧杂蒽
LiNH2SO3
Solvent-free
Aldehydes
Cyclohexane-1
3-dione
9-Aryl-1
2
3
4
5
6
7
8-octahydroxanthene-1
8-dione