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解整合素-金属蛋白酶33与哮喘发病关系研究进展 被引量：1

解整合素-金属蛋白酶33与哮喘发病关系研究进展
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摘要 哮喘是一种多基因遗传与环境因素共同作用的疾病[1-2]。解整合素-金属蛋白酶（adisintegrinandmetallo-proteinase,ADAM）33是一种新近发现的哮喘易感基因,是ADAM家族成员之一,该基因具有高度多态性,其单核苷酸多态性（singlenucleotidepolymorphisms,SNPs）与支气管哮喘的发生及气道高反应性可能存在相关性,是近年来的研究热点。本文就ADAM33与哮喘发病关系综述如下。
作者 刘肖君 乔红梅
机构地区 吉林大学第一医院儿科
出处 《中国实用儿科杂志》 CSCD 北大核心 2012年第3期223-225,共3页 Chinese Journal of Practical Pediatrics
基金 吉林省卫生厅重点实验课题
关键词 解整合素-金属蛋白酶33 支气管哮喘 单核苷酸多态性 气道高反应性 气道重塑 ADAM33 bronchial asthma single nucleotide polymorphisms airway hperresponsiveness airway remodeling
分类号 R72 [医药卫生—儿科]
  • 相关文献

参考文献26

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二级参考文献49

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共引文献27

同被引文献13

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  • 10宋颖芳,赖国祥,戚好文,吴昌归.1,25-二羟维生素D_3抑制被动致敏人气道平滑肌细胞的增殖[J].中国病理生理杂志,2011,27(9):1828-1831. 被引量：14

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二级引证文献17

中国实用儿科杂志
2012年 第3期

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