旋转式伽玛刀治疗颅内疾患455例分析

An Analysis of 455 Cases with Intracranial Lesions Treated by Gamma Knife

目的 旨在进一步提高伽玛刀治疗颅内疾病的效果。方法 分析研究颅内疾病的ＣＴ，ＭＲＩ以及病理性质及其周边结构的关系，拟定不同的治疗剂量，应用ＯＵＲ－ＸＧＤ旋转式伽玛刀进行治疗。结果 本组４５５例经ＯＵＲ－ＸＧＤ型伽玛刀治疗后，近期均无明显的不良反应。２１８例获得随访，其中显效４６例（２１．０％），有效１６５例（７５．７％），无效７例（３．２％）。结论 伽玛刀是神经外科的治疗手段之一。

Objective:To improve the therapeutic effect of Gamma knife on intracranial lesions.Methods:The CT and MRI images and pathological characteristics of intracranial lesions and their relationship with surrounding structures were analyzed.Different therapeutic dose was prescriped.Remedy was finished with OUR XGD rotating Gamma knife.Results:After treatment with OUR XGD rotating Gamma knife,no obviously immediate untoward effect was found in 455 cases.Follow up was achieved in 218 patients.Remarkable therapeutic effect was shown in 46 cases(21 0%),favorite result in 165 cases(75 7%),and no effect in 7 cases(3 2%).Conclusion:Gamma knife is one of the variable remedies in neurosurgery,and only after strict indication control,rational therapeutic dose prescription and suitable protection of correlating structures around the target can favorite clinical outcome be achieved.OUR XGD rotatng Gamma knife can be utilized to treat intracranial lesions safely and effectively because of stable mechanical property,excellent accuracy and high degree of automate.