摘要
目的研究复方丹参滴丸对冠脉慢血流患者的血管内皮功能的保护作用,探讨其机制。方法选择冠状动脉慢血流患者40例,患者知情同意,于冠脉造影术中采血5ml,检测ET、NO水平,然后给予复方丹参滴丸10丸/次,3次/d,服用3个月,观察临床症状缓解情况,再采血检测ET、NO水平,自身前后对照研究。结果治疗3月后患者临床胸痛症状较前明显缓解,血浆ET水平较治疗前明显降低(P<0.05),血浆NO水平较治疗前明显升高(P<0.05)。结论复方丹参滴丸能够缓解冠脉慢血流患者胸痛症状,调整、改善血管内皮功能的异常状态。
Objective To study the protective effect of Danshen Pill in vascular endothelium functions. Methods 40 patients with CSF were selected to carry out self - controled study. All patients were give the Danshen Pills, 10 pills/time,3 times/d, for 3 months. Plasma levels of ET and NO were tested in the two groups before and after 3 months. Results The symptoms of the patients were improved after treatment, NO was significantly increased and ET was significantly decreased after 3 months. ET level was significantly lower than before treatment （ P 〈 0. 05 ）, plasma NO levels significantly higher than that before treatment （ P 〈 0.05 ）. Conclusion Danshen Pills could adjust and improve the ab- normal conditions of vascular endothelium function.
出处
《中外医学研究》
2012年第6期8-9,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
