前列地尔治疗糖尿病下肢动脉粥样硬化闭塞症疗效观察

The clinical observation of DB artery of lower extremity scleratheroma block system by alprostadil

目的观察前列地尔治疗糖尿病下肢动脉粥样硬化闭塞症的临床疗效。方法回顾性分析110例糖尿病下肢动脉粥样硬化闭塞症患者临床资料，依据治疗方式不同分为观察组80例（常规治疗联合前列地尔）和对照组30例（常规治疗），比较两组治疗效果。结果观察组股动脉、胭动脉、胫后动脉及足背动脉的血管内径、血流量、血流峰时速度均明显优于对照组（均P〈0．05），观察组临床总有效率为100．0％，明显高于对照组的86．7％（x2=11．069，P〈0．05）。结论前列地尔治疗糖尿病下肢动脉粥样硬化闭塞症疗效明显，值得临床推广应用。

Objective To observe clinical effect of alprostadil on DB artery of lower extremity scleratheroma block system patients. Methods To retrospectively analyze clinical data of lower extremity scleratheroma block system patients in our hospital, which were divided into detection group and control group. Results The bore ,blood flow and Vdias of femoral artery,popliteal artery,arteria tibialis posterior and dorsal artery of foot of detection group were better than control group,the clinical total effective rate of detection group was higher than control group（P 〈0.05）, the difference was statistically significant. Conclusion The clinical curative effect of DB artery of lower extremity scleratheroma block system by alprostadil was obviously, which was worthy to be used.