交感神经皮肤反应检测在脑梗死患者自主神经损害评价中的应用

Application of sympathetic skin response detection in evaluate the autonomic nervous damage in patients with cerebral infarction

目的探讨交感神经皮肤反应（SSR）检测在评价脑梗死患者自主神经损害中的价值。方法对发病2周内的56例脑梗死组患者及50例条件匹配的健康对照者应用肌电图检测SSR，进行对比研究。结果脑梗死组18例SSR缺失，18例存在潜伏期或／和波幅异常，SSR异常率为64．29％，对照组SSR均正常，两组差异有统计学意义（t=10．66，3．83，均P〈0．01）。结论脑梗死后患者多数存在自主神经功能障碍，简单易行、安全无创的SSR可定量客观评价脑梗死患者的交感神经功能状态。

Objective To explore the value of sympathetic skin response （SSR） detection for evaluating the autonomic nervous damage in patients with cerebral infarction. Methods 56 cases with cerebral infarction within 2 weeks and 50 cases of healthy controls were detected SSR by EMG, and the results were compared. Results 18 patients with cerebral infarction did not elicit SSR and 18 patients were abnormal with the latency and amplitude of SSR, and the abnormality rate of SSR was accounting for 64. 29%, which was significantly different compared with control group（ t = 10.66,3.83, all P 〈 0.01 ）. Conclusion The patients with cerebral infarction had severe autonomic dysfunction and SSR, and SSR detection was a simple, safe and noninvasive method, and could quantitatively evaluate the sympathetic function in patients with cerebral infarction.