摘要
目的探讨血浆D-二聚体(D-D)、肌钙蛋白I(cTnI)联合检测在急性肺栓塞中的诊断价值。方法 D-二聚体用STAGOSTA Compact全自动血凝仪检测,cTnI用化学发光免疫法检测,仪器为罗氏电化学发光免疫分析仪,分别检测35例急性肺栓塞(APE)和40例正常健康人血浆中的D-二聚体和cTnI水平,所有数据用SPSS11.5软件包进行分析。结果急性肺栓塞患者血浆D-二聚体和cTnI水平均显著高于正常组,差异有统计学意义(P<0.05)。D-二聚体和cTnI单独检测APE的灵敏度分别为83.1、82.3%,特异度分别为36.7%、35.2%,两者联合检测APE的灵敏度为98%、特异度为58.3%。结论血浆D-二聚体、cTnI在APE诊断中具有重要临床意义,联合检测血浆中D-二聚体、cTnI的水平有利于提高急性肺栓塞的诊断率。
To evaluate the value of combined analysis of D-D,cTnI in the APE.Methods Plasma level of D-D in each patient was determined with STAGOSTA Compact,and Plasma levels of cTnI was determined in chemoluminescenco method.plasma levels of D-D and cTnI were collect from 35 cases with APE,40 cases helthy volunteers.Statistical analysis was performed by using SPSS 11.5.Results The concentration of D-D and cTnI in APE group were higher than those helthy volunteers group （P〈：0.05）.The sensitivity rates of D-D and cTnI in APE were 83.1,82.3,respectively, the specific rates were 36.7,35.2,respectively. In combined assay of D-D and cTnI,the sensitivity rate was 98 ,the specificity rate was 58.3 .comparing with the single assay, combined analysis had much higher diagnostic sensitivity.Conclusion The assay of D-D and cTnI is significant in diagnosis of APE.In Combined assay of D-D and cTnI can improve the rate of early APE.
出处
《中外医疗》
2012年第2期1-2,共2页
China & Foreign Medical Treatment
