他汀类药抗心房颤动的研究
摘要
心房颤动是临床上最常见的心律失常之一。临床和基础研究表明,他汀类药物具有减少心房纤颤发生、发展和复发的作用。其作用机制可能与抗炎、抗氧化、减少心房肌的结构重构和电重构、改善心脏自主神经功能等作用有关。
出处
《中外医疗》
2012年第3期135-137,共3页
China & Foreign Medical Treatment
参考文献23
-
1Hagiwars N.Inflammation and atrial fibrillation [J].Cire J,2010,74 (2):246- 247.
-
2Lin PH,Lee SH,Su CP,et al.Oxidative damage to mitochondrial DNA in atrial muscle of patients with atrial fibrillation [J].Free Radio Biol Med,2003,35(2):1310- 1318.
-
3Young-Xu Y, Jabbour S,Goldberg R,et al.Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease[J].Am J Cardiol,2003,92(12): 1379 - 1383.
-
4Hanna 1R,Heeke B,Bush H,et al.Lipid-lowering drug use is associ- ated with reduced prevalence of atrial fibrillation in patients with left ventricular systolic dysfunction[J].Heart Rhythm,2006,3(8): 881 - 886.
-
5Adabag AS,Nelson DB,Bloomfield HE.Effects of statin therapy on preventing atrial fibrillation in coronary disease and heart fail- ure [J].Am Heart J,2007,154(6):1140-1145.
-
6Dotani MI,Elnicki DM,Jain AC,et aLEffect of preoperative statin therapy and cardiac outcomes after coronary artery bypass grafting[J].Am J Cardiol,2000,86(10):1128 - 1130.
-
7Arribas-Leal JM,Pascual-Figal DA,Tomel-Osorio PL,et aI.Epide- miology and new predictors of atrial fibrillation after coronary surgery[J].Rev Esp CardioI,2007,60(80):841- 847.
-
8Patti G,Chello M,Candura D,et al.Randomized trial of atorvastatin for reduction of postoperative atrial fibrillation in patients under- going cardiac surgery:results of the ARMYDA-3(Atorvastatin for Reduction of Myocardial Dysrhythmia Atter cardiac surgery) study[J]. Circulation,2006,114( 14): 1455 - 1461.
-
9Kourliouros A,Valencia O,Hosseini MT,et al.Preoperative high- dose atorvastatin for prevention of atrial fibrillation after cardiac surgery:A randomized controlled trial [J].J Thorac Cardiovasc Surg, 2010(Epud ahead of print),1 11(1):244- 248.
-
10Virani SS,Nambi V, Razavi M,et al.Preoperative statin therapy is not associated with a decrease in the incidence of postoperative atrial fibrillation in patients undergoing cardiac surgery[J] .Am Heart J,2008,155(3):541 - 546.
二级参考文献10
-
1Frustaci A,Chimenti C,Bellocci F,et al.Histological substrate of atrial biopsies in patients with lone atrial fibrillation.Circulation,1997,96:1180-1184.
-
2Aviles RJ,Martin DO,Hassen CA,et al.Inflammation as a risk factor for atrial fibrillation.Circulation,2003,108:3006-3010.
-
3Scalia R,Gooszen ME,Jones SP,et al.Simvastatin exerts both anti-imflammatory and cardioprotective.Effects in apolipoprotein E-deficient mice.Circulation,2001,103:2598-2603.
-
4van de Ree MA,Huisman MV,Princen HMG,et al.Strong decrease of high sensitivity C-reactive protein with high-dose atovastatin in patients with type 2 diabetes mellitus.Atherosclerosis,2003,166:129-135.
-
5Li D,Fareh S,Leung TK,et al.Promotion of atrial fibrillation by heart failure in dog:atrial remodeling of a different sort.Circulation,1999,100:87-95.
-
6Mihm MJ,Yu F,Cames CA,et al.Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation.Circulation,2001,104:174-180.
-
7Chung MK,Martin DO,Sprecher D,et al.C-reactive protein elevation in patients with atrial arrhythmias.Circulation,2001,104:2886-2891.
-
8Lefer AM,Campbell B,Shin YK,et al.Simvastatin preserves the ischemic-reperfused myocardium in normocholerterolemic rat hearts.Circulation,1999,100:178-184.
-
9Xu YY,Jabbour S,Goldberg k,et al.Usefulness of station drugs in protecting against atrial fibrillation in patients with CorOnary artery disease.Am J Cardiol,2003,92:1379-1383.
-
10Gómez-Gerique JA,Ros Z,Olován J,et al.Effect of atorvastatin and bezafibrate on plasma levels of C-reactive protein in combined (mixed) hyperlipidemia.Atherosclerosis,2002,162:245-251.
共引文献20
-
1唐启卫.辛伐他汀在心房颤动中的应用(附46例报告)[J].中国厂矿医学,2005,18(5):432-432.
-
2吴立群,朱巍.他汀类药物的抗心律失常作用[J].临床内科杂志,2006,23(1):16-18. 被引量:8
-
3何友作,袁尚恒,刘正辉,杜松柏,高兴玉.辛伐他汀早期干预对急性冠脉综合征患者心功能和心律失常的影响[J].心脏杂志,2007,19(2):194-196. 被引量:2
-
4王少黎,费丽萍,郭艳霞,周宁.胺碘酮与辛伐他汀合用治疗老年人阵发性心房颤动的疗效分析[J].中华老年医学杂志,2007,26(6):453-454. 被引量:6
-
5王远龙,钟敬泉.他汀类药物在心房颤动治疗中的作用[J].心血管病学进展,2008,29(B05):54-56.
-
6黄冬,刘铭雅,李京波.他汀类药物预防心房颤动的作用[J].世界临床药物,2008,29(3):154-157. 被引量:2
-
7裴德安,黄进宇,徐正明,周智林.他汀类药物抗心律失常作用的研究[J].国际心血管病杂志,2008,35(4):232-236. 被引量:1
-
8丁超,傅向华.他汀类药物的抗心律失常作用研究进展[J].医学综述,2008,14(15):2323-2327. 被引量:3
-
9陈会校,何振山,李俊峡.他汀类药物的抗心律失常效应[J].华北国防医药,2008,20(5):66-69. 被引量:6
-
10范耀东.他汀类药物对心房颤动影响的研究进展[J].天津药学,2009,21(5):48-50. 被引量:12
-
1贺鹏康,周菁.心房颤动治疗新方向——延迟钠电流阻滞剂雷诺嗪[J].心血管病学进展,2015,36(1):1-3. 被引量:1
-
2邓婷智,尹微,欧柏青.血管紧张素Ⅱ受体拮抗剂抗心房颤动的研究进展[J].临床心血管病杂志,2010,26(1):4-6. 被引量:4
-
3殷跃辉,石伟.他汀类药物抗心房颤动作用[J].心血管病学进展,2008,29(1):141-143. 被引量:9
-
4何春杰,项美香.阿托伐他汀对慢性充血性心力衰竭合并阵发性心房颤动患者窦性心律维持及心功能的影响[J].心电与循环,2012,31(4):223-224. 被引量:4
-
5史晓静,陶贵周.不同剂量阿托伐他汀对老年冠心病合并心房颤动患者炎症因子及预后的影响[J].临床荟萃,2010,25(7):560-562. 被引量:5
-
6闫文菊,郭忠秀,张普,尹鲁骅,张焕轶.抗心房颤动起搏治疗阵发性心房颤动的临床疗效[J].中华临床医师杂志(电子版),2016,10(22):3337-3343. 被引量:2
-
7张健发,杨坤河,黄定,徐新娟,汤宝鹏,马依彤,张燕一.具有多种抗心房颤动模式起搏器的临床应用[J].国外医学(心血管疾病分册),2004,31(5):306-308. 被引量:2
-
8刘玉洁,张颖,陈刚,赵茹,孙根义.老年肥厚型心肌病心房颤动患者应用抗心房颤动起博器治疗成功一例[J].中华老年医学杂志,2008,27(2):128-128.
-
9刘红明,郭涛,赵玲,韩明华,刘中梅,肖践明,李淑敏,杨西云.抗心房颤动起搏器的应用初探[J].中国心脏起搏与心电生理杂志,2003,17(1):35-37. 被引量:3
-
10贺鹏康,霍勇,周菁,吴林.晚钠电流抑制剂对心房间传导的影响及其抗心房颤动作用的机制探讨[J].中华心律失常学杂志,2014,18(1):52-56. 被引量:10