摘要
本文应用血凝抑制试验(HI)对营南县262例流行性出血热(EHF)病人进行血清学分型。结果,230例为家鼠型(87.78%),29例为野鼠型(11.07%),未定型3例(1.15%)。褐家鼠EHF病毒抗原阳性率(16.65%)明显高于黑线姬鼠(8.11%)和大仓鼠(7.25%),表明该地是以家鼠型感染为主的混合型疫区。同时进行了临床与流行病学调查,家鼠型发病高峰为3~9月(67.83%),野鼠型多见于11月至翌年2月(58.62%),但两型病人全年各月均有发生,而且临床分型未见明显差异,轻、中、重和危重型均占有一定比例。
This paper reported that the seroloical typiug to the endemic area of epidemic hemorrhagic fever (EHF) in Junan of Shandong was done by hemag- glutination inhibition test. It was found that of 262 cases with EHF, 230 cases (87. 78%) were Rattus norvegicus type, 29 cases (11. 07%) were Apodemus agrarius type, 3 cases (1. 15%) were unidentified type. The EHF viral antigen positive rate (16%) in the lung of R. norvegicus was more than that (8. 11%) in the lung cf A. agrarius. It was proved to be the mixed endemic area where the type of R. norvegicns constituted the majority. Through clinical and epidemiological survey, we alse found that the epidemic peak of R. norvegicus type in the area was between March and June (67. 83%) and that of A. agrarius was between November and February (58. 60%), both of them onset in every month of the year. In addition, there was not re- markable difference in the clinical manifestation.