摘要
本研究用RPHI IFA-IgG检测拟诊HFRS患者82例156份血清,其中66例测出特异性抗体,非HFRS患者血清未出现假阳性反应。RPHI与IFA-IgG检测,恢复期血清比急性期血清呈4倍以上升高者分别为83.6％及73.8％,病程5天内血清阳性检出率为53.3％及41.9％。6—10天为95.8％及79.2％。两种试验的符合率为88.5％,阳性检出率比较x^2=9.39,P<0.01,RPHI非常显著高于IFA-IgG。
We detected HFRSV in 156 sera of 82 patients with HFRS diagnosed clinically by RPHI and IFA-IgG. 66 of 82 cases showed positive, and 83. 6% and 73. 8% of them were 4 times higher than those of acute stage in antibody titer of convalescent serum by RPHI and IFA-IgG, respec- tively. There were no false-positive results in 256 normal sera. The positivity rates of detecting anti- bodies during the first five days after onset by RPHI and IFA-IgG were 53. 3% and 41. 9% respe- ctively, and 95. 8%, 79. 2% in the second five days. The positivity rate of RPHI was significant higher than those of IFA-IgG (x^2=9. 39, P<0. 01). The GMT of RPHI and IFA-IgG were 120 and 102. The CV were 18. 0% and 13. 3%, respectively.
