枳椇子提取物对低压缺氧环境下小鼠游泳的影响

Effect of Hovenia Dulcis Thunb Extracts on Tolerance Time of Exhaustion in Swimming Test under Low Pressure and Hypoxia

目的考察枳椇子提取物对低压缺氧环境下小鼠游泳至力竭时间的影响。方法雄性ICR小鼠随机分为8组,分别为空白对照组、诺迪康胶囊阳性药组、枳椇子提取物1〔200、100、50 mg/(kg.d)〕和枳椇子提取物2〔32、16、8 mg/(kg.d)〕高、中、低各3个剂量组,连续给药5 d后进行低压缺氧下游泳实验。结果枳椇子提取物能够延长低压缺氧环境下小鼠游泳至力竭时间。结论低压缺氧环境下枳椇子提取物能够延缓机体运动性疲劳。

Objective To observe the effect of extracts from Hovenia dulcis thunb on the tolerance time of exhaustion of mice in swimming test under low pressure and hypoxia.Methods Male ICR mice were randomly divided into 8 groups at blank group,Nuodikang capsule positive group,three groups of Hovenia dulcis Thunb extracts 1 and 2 at high,middle and low dosage.The mice were treated consecutively for 5 and then the swimming test was performed.Results Hovenia dulcis Thunb extracts could extend the tolerance time of exhaustion in swimming test under low pressure and hypoxia.Conclusion Hovenia dulcis Thunb Extracts can help relieve the exercise fatigue under low pressure and hypoxia.