贵州地区体检人群高尿酸血症流行病学研究

Study on the prevalence of hyperuricemia and metabolic syndrome in the senior of Guizhou

目的探讨贵州地区20岁以上人群的高尿酸血症的发病情况。方法对我院2009年到2011年期间到我院进行体检的健康人群2 616例,于空腹静脉抽血查血糖、血脂、血尿酸、肾功能等,并作身高、体重、血压等测定。结果2 616例体检人群,男性1 929例,女性686例。高尿酸血症共551例,占总抽样人群21.06%,其中女性74例,占10.79%,男性477例,占24.73%。男女两组组间比较差异具有显著性(χ2=59.38,P<0.05)。男性血尿酸均值显著高于女性(t=30.23,P<0.05),女性在50岁以后血尿酸水平逐渐升高接近男性。男性高尿酸血症组年龄显著高于女性组(t=3.773,P<0.05)。高尿酸人群中患高血糖、高血压、超重、高脂血症的患病率显著高于总体人群(P<0.05)。结论贵州地区体检人群高尿酸血症较高。男性的高尿酸血症发病率高于女性,女性于更年期后血尿酸发病率逐渐接近男性。体重指数超标、高血压、高血糖、高脂血症是高尿酸血症的重要相关因素。

Objective To ascertain the prevalence of hyperuricemia and metabolic syndrome in the seniors （age〉20） in Guizhou. Methods The past urine acid, lipids, glucose, blood pressures and body weight of the healthy senior in 2 616 participants were checked up, who were the regular health exami- nation of our hospital from 2009 to 2011. Results There were 1 929 male and 686 female in 2 616 par- ticipants. The results shown that 551 hyperuricemia and amounted to 21.06%. In the hyperuricemia, there were 477 male （24.73%）and 74 female （10.77%）were accounted. There were significant differ- ences statistically in comparison between male and female （X2=59.38, P〈0.05）. Urine acid level of male were higher than female and there were significant differences statistically （t= 30.23, P〈0.05）. Positive correlation was found between hyperuricemia and factors including over weight,hypertention, diabetes, hyperlipidemia. Conclusion The incidence of hyperuricemia is higher in Guizhou. Over weight, diabetes, hypertention and dyslipidemia are important factors of hyperuricemia.