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神经生长因子治疗周围神经病变临床疗效分析 被引量:7

The Clinical Efficacy Analysis of the Nerve Growth Factor in the Treatment of Peripheral Neuropathy
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摘要 目的:探讨神经生长因子治疗周围神经病变的临床疗效。方法:将周围神经病变患者随机分为神经生长因子治疗组和非神经生长因子治疗组,神经生长因子治疗组在常规治疗基础上加神经生长因子(苏肽生)肌肉注射。结果:神经生长因子治疗组在治疗后,面神经MNCV、三叉神经SNCV、正中神经MNCV、正中神经SNCV等4项有显著变化。结论:周围神经病变病例加神经生长因子(苏肽生)肌肉注射,取得了满意疗效。 Objective: To evaluate the clinical efficacy of the nerve growth factors in the treatment of peripheral neuropathy.Methods: The peripheral neuropathy patients were randomly divided into the nerve growth factor treatment group and the control group without nerve growth factor treatment.The nerve growth factor treatment group was given nerve growth factors(Su peptide Health) intramuscularly in addition to conventional treatment.Results: In the nerve growth factor treatment group,there were significant changes in the facial nerve MNCV,trigeminal nerve SNCV,median nerve MNCV and in median nerve SNCV after treatment.Conclusion: Satisfactory curative effects can be achieved with nerve growth factor(Su peptide Health) intramuscular injection in the cases of peripheral neuropathy.
作者 张沛 高励
出处 《包头医学院学报》 CAS 2012年第1期54-56,共3页 Journal of Baotou Medical College
关键词 神经生长因子 周围神经病变 临床疗效 Nerve growth factors Peripheral Neuropathy Clinical Efficacy
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参考文献7

  • 1陈扬,郑茂荣.疱疹后遗神经痛发病机理与治疗的研究进展[J].国外医学(皮肤性病学分册),2002,28(1):49-51. 被引量:114
  • 2中华神经精神科杂志编委会.脱髓鞘病的诊断标准[J].中华神经精神科杂志,1994,27(6):380-380.
  • 3Jacobs WB, Fehlings MQ. The molecular basis of neural re- generation[ J]. Neurosurgery,2003,53 (4) :943 - 948.
  • 4George A, Buehl A, Sommer C. Wallerian degeneration after crush injury of ralsciatic nerve increases endo - and epi- neurial tumor necrosis factor - alpha protein [ J ]. Neurosei Lett ,2004,372 (3) :215 - 219.
  • 5张杰,薛宏斌.周围神经损伤后修复再生机制的研究进展[J].医学信息,2010,23(6):1759-1760. 被引量:11
  • 6Nurcomb V, Hiu MA, Eagleson L, et al. Motor neuron survival and neuritic extension from spinal cord explants in- duced by factors released from denervated muscle [ J ]. BrainRes, 1984,291 ( 1 ) : 19 - 28.
  • 7王占友,石玉秀.神经生长因子与运动神经再生[J].解剖科学进展,1997,3(2):126-129. 被引量:13

二级参考文献18

  • 1Seckel BR.Enhancement of peripheral nerve regeneration.Mucscle Nerve,1990,13:785-791.
  • 2Mendell LM.Neurotrophins and sensory:role in development,mainte2 nance and injury.Biol Sci,1996,26:351-363.
  • 3Jeffrey L,Goldberg,Ben A.The relationship between neuronal survival and regenaration[J].Annu.Rev.Neurosei,2000,23:579-612.
  • 4Einheber S,Hannock MJ,Metz CN,et al.Transforming growth factor-betal regulates axon/schwann cell interactions[J].Cell Biol.1995 Apr,129(2):443-58.
  • 5Jacobs WB,Fehlings MQ The molecular basis of neural regeneration[J].Neurosurgery.2003 Oct,53(4):943-48.
  • 6George A,Buehl A Sommer C.Wallerian degeneration after crush injury of rat sciatic nerve increases endo-and epineurial tumor necrosis factor-alpha rotein[J].Neurosei Lett.2004 Dec 6,372(3):215-9.
  • 7Chao MV.Neurotrophin and their receptors:a convergence point for many signaling pathways[J].Nature Rev Neurosci.2003,4:299-309.
  • 8Lambert WS,Clark AF,Wordinger RG et al.Effect of exogenous neurotrophins on Trk receptor phosphorylation,cell proliferation,and neurotrophin secretion by cells isolated from the human lamina cribrosa[J].Mol Vis.2004 Apr 19,10:289-96.
  • 9Hari A,Djohar B,Skutella T et al.Neurotrophins and extracellular matrix molecules modulate sensory axoll outgrowth[J].Int J Dev Neurosci.200,22(2):113-7.
  • 10Lee Sk,Wolfe SW.Peripheral nerve injury and repair.J Am Acad Orthop surg,2000,4:243-252.

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