摘要
目的:研究叶瓜参化学成分。方法:对叶瓜参的65%乙醇提取物中小极性部分进行行分离纯化,得到脑苷脂分子种3,对脑苷脂分子种3应用高效液相色谱进一步分离纯化,得到3个脑苷脂单体,CF-3-1(1)、CF-3-2(2)和CF-3-3(3)。结果:根据化合物的波谱数据和化学方法鉴定了其结构。结论:三个化合物为首次从叶瓜参中分离得到,首次得到化合物2和3的单体化合物。
AIM： To study the chemical constituents of Monochasma savatierii Franch.. METHODS： The chemical constituents were isolated and repeatedly purified by column chromatography with silica gel, Rp-C18, Sephadex LH-20 and identified by IR, MS and NMR. RESULTS AND： Eight compounds were obtained and identified as 7, 8-dehydroboschnialactone （1）, argyol （2）, liquirti-genin （3）, β-sitosterol （4）, p-hydroxycinnamic acid （5）, 2-hydroxy-4-methoxybenzonic acid （6）, p-hydroxyphenylethanol （7）, proto-catechuic acid （8）. CONCLUSION： Compound 1 was obtained from natural source for the first time and the others have been isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
2012年第2期105-109,共5页
基金
supported by International Science and Technology Cooperation Project of China (No.2010DFB30810)~~
关键词
鞘糖脂
脑苷脂
海参
叶瓜参
Glycosphingofipids
Cerebrosides
Sea Cucumber
Cucumariafrondosa
