期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

注射Azadirachta indica水提物对大鼠血红蛋白和血糖含量的影响(英文)

Changes of hemoglobin content and glucose levels in the blood of Rattus norvegicus by water extracts of Azadirachta indica
原文传递
导出
摘要 Presently, there is a growing interest in herbal remedies. Neem (Azadirachta indica) has been used in traditional medicine over centuries. In the present study, the effects of water extracts of Azadirachta indica seeds, stems, flowers and bark on the changes of hemoglobin content (Hb) and glucose levels in the blood of Rattus norvegicus were investigated. Different doses of A. indica water extracts of seeds, stems, flowers and bark were injected to the tested animals every 48 h for 14 days. Significant decrease in both hemoglobin content and glucose levels in the blood samples in all groups of injected rats were compared to control group. However, in all groups higher decrease was shown in the rats injected with 1 g·mL-1 of A. indica water extracts. In addition, the present study showed no significant relationship between decreased hemoglobin content and glucose levels in blood samples, and increased doses injected. In conclusion, A. indica has the potential to decrease both hemoglobin content and blood glucose levels. Presently, there is a growing interest in herbal remedies. Neem （Azadirachta indica） has been used in traditional medicine over centuries. In the present study, the effects of water extracts of Azadirachta indica seeds, stems, flowers and bark on the changes of hemoglobin content （Hb） and glucose levels in the blood of Rattus norvegicus were investigated. Different doses of A. indica water extracts of seeds, stems, flowers and bark were injected to the tested animals every 48 h for 14 days. Significant decrease in both hemoglobin content and glucose levels in the blood samples in all groups of injected rats were compared to control group. However, in all groups higher decrease was shown in the rats injected with 1 g·mL-1 of A. indica water extracts. In addition, the present study showed no significant relationship between decreased hemoglobin content and glucose levels in blood samples, and increased doses injected. In conclusion, A. indica has the potential to decrease both hemoglobin content and blood glucose levels.
作者 Shori Amal Bakr shori_7506@hotmail.com
机构地区 Division of Biology
出处 《中国天然药物》 SCIE CAS CSCD 2012年第2期135-137,共3页
关键词 Azadirachta indica Rats Blood glucose HEMOGLOBIN Azadirachta indica Rats, Blood glucose Hemoglobin
分类号 R965 [医药卫生—药理学]
  • 相关文献

参考文献29

  • 1Winslow LC, Kroll DJ. Herbs as medicine [J]. Arch intern Med, 1998, 158(20): 2192-2199.
  • 2Alam MM, Siddiqui MB, Husain W, et al. Treatment of diabetes through herbal drugs in rural India [J], Fitoterapia, 1990,61(3): 240-242.
  • 3Biswas K, Chattopadhyay I, Banerjee RK, et al. Biological activities and medicinal properties of Neem (Azadirachta in- dica) [J]. Curr Sci India, 2002, 82(11): 1336-1345.
  • 4Singh PP, Junnarkar AY, Thomas GP, et al. A pharmacological study of Azadirachta indica [J]. Fitoterapia, 1990, 61: 164-168.
  • 5Harish KG, Vidya PR, Vinothini G, et al. The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis [J]. Invest New Drugs, 2008, 27(3): 246-52.
  • 6Bandyopadhyay U, Biswas k, Sengupta A, et al. Clinical studies on the effect of Neem (Azadirachta indica) bark extract on gastric secretion and gastroduodenal ulcer [J]. Life Sci, 2004,75(24): 2867-2878.
  • 7Garg S, Taluja V, Upadhyay SN, et al. Studies on the contraceptive efficacy of Praneem polyherbal cream [J]. Contracep- tion, 1993, 48(6): 591-596.
  • 8Karmakar PR, Chatterjee BP. Isolation and characterization of two IgE-reactive proteins from Azadirachta indica pollen [J]. Mol Cell Biochem, 1994, 131(1): 87-96 (abstract).
  • 9Chattopadhyay RR. Hypolipidemic activity of Azadirachta indica leaf extract in rats [J]. Proc Indian Nat Sci Acad B, 1995,61: 281–284.
  • 10Sharma HC, Sankaram AVB, Nwanze KF, et al. Utilization of natural pesticides derived from neem and custard apple in in- tegrated pest management. In :Azadirachta indica A. Juss. Singh RP, and Saxena RC,(eds.) [M]. New Delhi: Oxford & IBH Publishing Co., 1999: 199-211.
中国天然药物
2012年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部