稀土上转换发光纳米材料的应用

Rare-Earth Upconversion Nanophosphors

稀土上转换发光纳米材料(简称UCNPs)不仅光稳定性强、发射带窄、荧光寿命长、化学稳定性高、潜在生物毒性低,而且采用近红外连续激发光源激发还使其具有较大的光穿透深度、无光闪烁和光漂白、无生物组织自发荧光以及对生物组织几乎无损伤等显著优点,已经成为当前很多领域乃至交叉科学的应用研究热点。由于氟化物基质的UCNPs具有较高的发光效率,本文首先归纳总结了近年来氟化物UCNPs的主要合成及表面改性方法,然后重点综述了近年来UCNPs在免疫分析及生物传感、生物成像、载药、光动力理疗及热致理疗、光导开关和信息存储以及太阳能电池等方面的研究与应用进展。

Rare-earth upconversion nanophosphors （UCNPs） have attracted significant attention benefited from their unique properties, such as strong photostability, narrow emission band, long fluorescent lifetime, high chemical stability, and low potential cytotoxicity, etc. Furthermore, being photoexcitable via continuous near infrared （NIR） radiation renders them superior performances, such as great light penetration depth, absence of photobleaching and photoblinking, lack of tissue autofluorescence, and less harmful to biological specimens. Recently, startling research interests have been ascribed to UCNPs, especially fluoride hosts-based UCNPs which are most efficient known to date, among various even interdisciplinary sciences field. Herein, recent synthesis and surface modification methodologies are outlined and summarized. Then the latest advances on research and applications of UCNPs are highlighted and reviewed, including immunoassay, photodynamic therapy, photothermal therapy, light induced switching, data storage, bioimaging, drug delivery, and solar cells, etc.