基于矩阵分析法的慢性萎缩性胃炎辨证论治疗效评价研究

Comparison on String-Like Pulse Figure Parameters between Hypertension and Non-Hypertension Cases

目的：探索矩阵分析法在中医辨证论治疗效评价中的应用。方法：以慢性萎缩性胃炎（CAG）为范例,临床选择经＂虚实标本证候辨识数据库＂辨识的CAG 5种虚实相兼证候共100例,采用补虚泻实、标本兼治的证治方法治疗,半年为一疗程,疗程结束后采用证候矩阵、治疗矩阵、效果矩阵模型的变量测算及误差矩阵推导,推算出疗效值。结果：虚实标本辨治慢性萎缩性胃炎总体症状的疗效为0.4~0.6,具有统计学意义（P〈0.05）。结论：初步表明矩阵分析法可用于中医辨证论治的疗效评价。

This study was aimed to analyze pulse with time-domain analysis method in the comparison of string-like pulse figure parameters between hypertension and non-hypertension cases.The hemodynamics changes and formation mechanism between two kinds of string-like pulses were also initially inferred.The string-like pulse figure of 224 primary hypertension cases and 300 non-hypertension cases were collected and compared with the ZBOX-1 Pulse Condition Instrument.The time-domain parameters（h3/h1,h4/h1,w/t） were compared for hypertension string-like pulse and non-hypertension string-like pulse.The result showed that the h3/h1 value of string-like pulse of both hypertension and non-hypertension group is significantly higher than the healthy group（P0.01）;and the h3/h1 value of hypertension group is significantly higher than non-hypertension group（P0.01）;the h4/h1 value of hypertension group is significantly higher than non-hypertension and healthy groups（P0.01）;the w/t value of both hypertension and non-hypertension group are significantly higher than the healthy group（P0.01）.It was concluded that the string-like pulse group of hypertension has high peripheral resistance,poor blood vessel elasticity and increased arterial tension.The string-like pulse group of non-hypertension has no significant changes in peripheral resistance.But the arterial compliance in non-hypertension group has been decreased.The main arteries are at high pressure and high tension status.Both of them have different blood dynamics basis.