米索前列醇预防产后出血的临床观察

目的：观察米索前列醇用于剖宫产预防产后出血的效果。方法：选择160例剖宫产产妇，随机分为实验组和对照组。对照组80例，胎儿娩出后宫体肌内注射缩宫素20IU，再静脉滴注缩宫素20IU。实验组80例，胎儿娩出后宫体肌内注射缩宫素20IU，手术结束时阴道后穹隆放置米索前列醇600μg；以上各组观察产后2小时及产后24小时出血量。结果：产后2小时出血量实验组平均为（160±23）ml对照组为（288±56）ml有显著性差异（P〈0．05）。结论：米索前列醇促进子宫收缩作用强于缩宫素，能较好地预防剖宫产后出血，且用药方便、安全。

Objective： To observe misoprostol for prevention of postpartum hemorrhage of cesarean section. Methods： 160 cases of cesarean section were randomly divided into experimental and control group. Control group, 80 patients, intramuscular injection of fetus body temple oxytocin 20IU, then intravenous infusion of oxytocin 20IU. Experimental group of 80 patients, intramuscular injection of fetus body temple oxytocin 20IU, after the end of surgery, vaginal misoprostol dome 600 μ g; over 2 hours of each set of observations and postpartum hemorrhage 24 hours of delivery. Results： Postpartum hemorrhage in experimental group 2 hours on average （160 ±23） ml in control group （308 ±56） m, 1 There was a significant difference （P 〈0.05）. Conclusion： Misoprostol for uterine contraction was stronger than that of oxytocin, can better prevent bleeding after cesarean section, and the drug easily and safely.