2型糖尿病合并心房纤颤患者NT—pro BNP的变化及意义
摘要
目的：探讨2型糖尿病合并房颤患者血清NT—pro BNP水平及其临床意义。方法：对我院2009年1月至2011年12月收治的2型糖尿病患者228例，其中单纯2型糖尿病患者108例（A组）、2型糖尿病合并阵发性房颤患者52例（B组）、2型糖尿病合并持续性房颤患者68例（C组），测定其血浆NT—pro BNP水平、左房内径（LA）、EF值。结果：持续性房颤组的NT—pro BNP（876．23±31．67pg／mLvs．546．18±26．58pg／mL）与LA（48．4±9．5mm vs．40．3±5．2mm）高于阵发性房颤组（P〈0．01）；阵发性房颤组患者的NT—pro BNP（546．18±26．58pg／mLvs．124．06±38．73pg／mL）与LA（40．3±5．2mmvs．36．4±4．3mm）高于非房颤组（P〈0．01）。Logistic回归分析表明，糖尿病患者血清NT—pro BNP水平越高，房颤的可能性增大。结论：糖尿病合并房颤患者NT—pro BNP水平升高，NT-pro BNP及LA可预测糖尿病患者发生房颤的潜在风险。
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