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蛋白激酶B与乳腺癌的最新研究进展 被引量：1

The latest research advances in protein kinase B and breast cancer
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摘要 丝氨酸/苏氨酸蛋白激酶即蛋白激酶B(protein kinase B,PKB/Akt)是细胞内最重要的激酶之一,它能够通过接受整合多种细胞外信号产生多种生物学效应,包括对细胞增殖、迁徙、生长、周期、能量代谢、死亡等多方面的影响。Akt在乳腺癌发展过程中的作用成为研究热点。现就近两年来Akt与乳腺癌的重要研究成果予以综述。 The protein serine/threonine kinase Akt,also known as protein kinase B（PKB）,is one of the most important kinases in cell.Akt integrates a plethora of extracellular signals to generate diverse outcomes,including proliferation,motility,growth,cell cycle,glucose homeostasis,and cell death.What is the role of Akt in the breast cancer has become a research focus.In this review,we will show the most important and latest research about Akt with breast cancer.
作者 张超 孙治君
机构地区 重庆医科大学附属第二医院乳腺甲状腺外科
出处 《现代肿瘤医学》 CAS 2012年第3期622-624,共3页 Journal of Modern Oncology
基金 重庆市科技攻关项目(编号:CSTC 2008AC5082)
关键词 蛋白激酶B 乳腺癌 进展 Akt breast cancer advance
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献25

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共引文献2

同被引文献16

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现代肿瘤医学
2012年 第3期

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