135例皮肤鳞状细胞癌发病相关因素回顾性分析

Retrospectively Analysis on Factors Related to 135 Cases of Skin Squamous Cell Carcinoma

目的通过对近7年来皮肤鳞状细胞癌发生情况及发病相关因素的分析,从而反映该院所属地区的皮肤鳞状细胞癌发病情况及发病原因,为进一步临床研究提供参考。方法对2004年1月—2010年12月华西医院烧伤整形科收治的135例皮肤鳞状细胞癌患者临床资料进行回顾性分析。结果近7年来皮肤鳞状细胞癌患病人数逐渐增加,好发年龄为50～59岁(35.56%),其中在文化程度较低尤其在农民中发病率明显高于文化程度较高及其他职业者(P<0.05)。多数患者在慢性溃疡(17.04%)、瘢痕(17.04%)及各种外源性刺激后(28.15%)发病,分化程度与原发疾病之间无明显差异性。结论本地区的皮肤鳞状细胞癌的发病人数在逐年增加,皮肤鳞状细胞癌的发生是由一种或多种因素综合作用的结果,与外源性损伤关系较为密切。

Objective To analyse the morbidity and the factors which related to skin squamous cell carcinoma（SCC） in recent seven years.Thus reflect the occurrences and reasons of the skin SCC of the subordinate area,offer more information for further clinical research.Methods 135 cases of skin SCC from January 2004 to December 2010 in department of burns and plastic surgery in west China hospital were analysed retrospectively.Results The number of patients suffered from skin SCC was increased gradually in the past seven years,that occurred almost in 50~59 years old（35.56%）.These groups with lower cultural level especially peasants had higher incidence than the well educated person and people of other professions（P0.05）.Most of the patients had chronic ulcer（17.04%）,scar（17.04%）,also various kinds of external stimulation（28.15%）.And these took an important role in the incidence.Conclusion The number of patients with skin SCC increases gradually year by year in this area.The final differentiation degrees have no obvious relevance to the primary diseases.