强直性脊柱炎伴发葡萄膜炎的临床特点和中西医结合治疗

Clinical characteristics of uveitis associated with ankylosing spondylitis and integrated treatment of traditional Chinese and western medicine

目的观察强直性脊柱炎(ankylosing spondylitis,AS)伴发葡萄膜炎的临床表现和中西医结合治疗的效果。方法中西医结合治疗AS伴发葡萄膜炎患者29例(34只眼),对其临床表现和治疗效果进行回顾性分析。结果 1.性别与发病年龄:男28例,女1例;AS平均发病年龄27岁,葡萄膜炎平均发病年龄33岁。2.临床表现:29例患者均有腰骶部不适,X线检查提示骶髂关节炎,葡萄膜炎发作时腰骶部不适加重;26例28只眼为非肉芽肿性前部葡萄膜炎,双眼交替发作;3例6只眼为全葡萄膜炎。3.治疗效果:治疗后视力提高,眼部炎症消失,腰骶部不适减轻。结论 AS伴发的葡萄膜炎有一定的特点,中西医结合治疗有效。

OBJECTIVE To observe clinical manifestations and treatment efficacy with combination of traditional Chinese and western medicine of uveitis associated with ankylosing spondylitis（AS）.METHODS Twenty-nine uveitis patients（34 eyes）associated with AS were retrospectively analyzed.RESULTS 1.Gender and age of onset： 28 patients were male,1 was female;the average age of AS patients was 27years old,and the average age of uveitis was 33 years old.2.Clinical manifestations： All of the 29 patients had lumbosacral discomfort,and all patients had radiological evidences of sacroiliitis.When uveitis outbroke,lumbosacral discomfort increased;when patients were examined,26 patients（28 eyes）had anterior uveitis and non-granulomatous uveitis.Both eyes were attacked in turn.Three patients（6 eyes）had panuveitis.3.The treatment effect： after treatment,vision improved,eye inflammation disappeared,and lumbosacral discomfort reduced.CONCLUSIONS Uveitis associated with AS has certain characteristics,and could be effectively treated by combination of traditional Chinese and western medicine