2005-2011年山东省流行性感冒监测结果与分析

Surveillance of influenza in Shandong province,2005-2011

目的掌握2005-2011年山东省流行性感冒(流感)流行规律,病毒型别及其活动水平,为流感的监测预警提供信息。方法收集2005-2011年山东省流感监测系统流感样病例(ILI)监测资料和ILI鼻咽拭子标本的流感病毒检测结果资料进行分析。结果 2005-2011年6个年度,哨点医院内科(儿内科)门诊患者合计9 729 498例,其中ILI 246 904例,占2.54%。6个年度ILI%分别为2.78%、2.02%、1.82%、2.05%、3.84%和2.24%(P<0.05);70.59%的ILI集中在5岁以下年龄组。合计检测ILI标本10 901份,检出流感病毒1563株,阳性率为14.3%。6个年度流感病毒检测阳性率分别为13.8%、19.2%、26.4%、13.7%、24.8%和5.5%(P<0.05)。对ILI%与病毒分离率两条序列进行等级相关分析,相关系数为0.293(P<0.05),呈正相关。结论 2009-2010年流感病毒较为活跃,6个监测年度中流感优势毒株亚型之间呈交替变化趋势并有一定的规律,ILI流行特征与流感病毒活动趋势基本一致。

Objective To understand the disease trend,virus type and activity level of influenza in Shandong from 2005 to 2011and provide scientific information for the surveillance and early warning of influenza.Methods The surveillance data of influenza like illness（ILI） and the detection results of ILI cases＇ nasal swabs during this period were collected to conduct analysis.Results From 2005 to 2011,a total of 9 729 498 outpatients visited sentinel hospitals,of which 246 904 were ILI cases,accounting for 2.54%.The annual proportion of ILI cases was 2.78%,2.02%,1.82%,2.05%,3.84%,and 2.24%,respectively（P0.05）.Up to 70.59% of ILI cases were children aged 0-5 years.Totally 10 901 samples from ILI cases were detected and 1563 strains of influenza viruses were isolated（14.3%）.The annual positive rate was 13.8%,19.2%,26.4%,13.7%,24.8% and 5.5% respectively（P0.05）.Spearman correlation analysis indicated that ILI rate and isolation rate of virus strain was positive correlated（r=0.293,P0.05）.Conclusion Influenza virus was more active in 2009.The predominant strains changed regularly,The ILI incidence characteristics was similar to influenza virus activity.