摘要
用离体大鼠心脏缺血后再灌注模型,根据心肌亚微结构改变及线粒体比表面测定,揭示金属硫蛋白对缺血后再灌注损伤有明显保护作用,提示金属硫蛋白是一种细胞保护剂,可望用于临床,控制缺血后再灌注损伤。
Using a model of postischemic reperfusion of isolated rat hearts, protective effect of m etallothio-nein on postischemic reperfusion injury has been found by studying changes in myocardium ultrastruc-ture and specific surface of mitochondria. The results show that metallothionein is a cell protective drug and it is hopeful to be used to protect myocardium against postischemic reperfusion injury.
出处
《北京医科大学学报》
CSCD
1989年第2期101-1,177,共1页
Journal of Peking University(Health Sciences)
关键词
金属硫蛋白
心肌缺血
再灌注损伤
Metallothionein Postischemic reperfusion injury Mitochondria specific surface Cell protection
