妊娠期牙龈炎患者龈沟液中天门冬氨酸转氨酶和碱性磷酸酶的含量变化

Contents comparison of AST and ALP in gingival crevicular fluid from pregnant women with or without pregnancy gingivitis

目的:比较妊娠期牙龈炎患者和正常妊娠妇女龈沟液中天门冬氨酸转氨酶(AST)和碱性磷酸酶(ALP)水平的变化,探讨AST和ALP在妊娠期牙龈炎中的作用。方法:采集30例妊娠期牙龈炎患者和30例正常妊娠妇女龈沟液,处理后采用全自动生化分析仪分析AST和ALP含量,并做统计学分析。结果:妊娠期牙龈炎患者龈沟液中AST和ALP含量均显著高于正常妊娠妇女龈沟液中的含量,有统计学差异(P<0.01)。结论:在妊娠期牙龈炎的发生发展过程中,AST和ALP发挥了重要的致炎作用,AST、ALP可以作为提示炎症活跃的信号分子。

Objectine： To investigate the effect of aspartate transaminase （AST） and alkaline phosphatase （ALP） in pregnancy gingivitis by comparing the levels of AST and ALP in gingival crevicular fluid from pregnant women with or without pregnancy gingivitis. Method： Gingival crevicular fluid from 30 pregnant women with pregnancy gingivitis and 30 pregnant women without pregnancy gingivitis were harvested respectively, then analyzed the levels of AST and ALP by automatic biochemistry analyzer after special treatment and performed statistical analysis. Result： Levels of AST and ALP in gingival crevicular fluid from pregnant women with pregnancy gingivitis were significantly higher than those from pregnant women without pregnancy gingivitis and statistical difference could be detected, P 〈0.01. Conclusion： AST and ALP play important roles in pregnancy gingivitis and could be regard as signaling molecules of active inflammation.