妊娠合并甲型H_1N_1流感14例临床分析

Clinical Analysis of Pregnancy with Infection A H_1N_1 Influenza

目的:探讨妊娠合并甲型H1N1流感的临床特点、治疗及其结局。方法:对2009年11月2日至2009年12月2日我院救治的14例妊娠期感染H1N1流感孕妇的临床情况进行总结性分析。结果:14例孕妇住院3～21天,平均8.6天。4例继续妊娠,7例手术结束妊娠,1例引产,2例自娩。13例新生儿存活,1例死亡,存活新生儿中5例早产,无新生儿H1N1感染病例,无孕妇死亡病例。结论:妊娠期感染H1N1流感孕妇更容易出现呼吸困难症状,病理妊娠及妊娠合并内科疾病者更易成为危重症病例。而早期应用奥司他韦能有效促进病情恢复,并未发现有母儿不良结局。

Objective：To explore the clinical characteristics, treatment and outcome of A H1N1 influenza infection in women with pregnancy. Methods：14 pregnancy women infected A H1N1 influenza in our hospital from November 2 to December 2 2009 were enrolled, and their clinical characteristics were analyzed. Re- sults：14 pregnant women stayed at hospital for 8.6 days in average （ranging from 3 to 21 days）. For preg- nancy outcomes, 4 cases continued pregnancy, 7 cases were terminated by cesarean section, and onechose induced abortion, and two had vaginal delivery. For neonatal outcomes, 13 newborns survived （5 premature newborns）, and one neonatal death. No newborn acquired A H1N1 infection, and no maternal death was observed. Conclusions：Pregnant women with H1 N1 influenza infection had dyspnea more fre- quently. Pathological pregnancy and pregnancy combined medical disease seemed to be more severe. The early use of oseltamivir may promote recovery effectively, and no adverse events were observed either in maternal side or newborn side.