转基因动物生物安全研究与评价

Biosafety assessment of genetically engineered animals:a review

随着转基因动物在新品种培育、异种器官移植、生物反应器和疾病模型等方面的研究与发展,转基因动物的生物安全性引起了人们的广泛关注。目前,各国政府与机构已制定了相应的法律法规来规范转基因动物的研究与应用。文中介绍了转基因动物生物安全研究的内容、评价原则、评价政策与程序、上市或有望上市的转基因动物产品。最后,对转基因动物及其产品的研究与应用进行了展望。

With the research and development of genetically engineered animals（GEAs） in breeding of new variety,xenotransplantation,bioreactor and disease model,biosafety issues of GEAs have attracted widespread attentions worldwide.So far,governments and agencies have established corresponding laws and regulations to regulate research and application of GEAs or their derived products.We reviewed research contents,evaluated principles,policies and procedures for biosafety of GEAs,also enumerated upcoming approved products of GEAs.Finally,we suggested perspectives of research and application of GEAs or their derived products.