胎儿宫内生长受限胎盘组织中胰岛素样生长因子Ⅰ受体/MAPK信号通路异常的研究
摘要
胎儿宫内生长受限（FGR）的发生率为4%～7%,明显增加新生儿在围生期的死亡率（4～6倍）[1]。目前胎儿宫内生长受限的发病机理尚不清楚,近年来,胰岛素或胰岛素样生长因子（IGF）及其受体（IGF-R）分泌和功能的失调成为目前研究的重点[2]。胰岛素样生长因子在细胞的分化、增殖、个体的生长发育中具有重要的促进作用。
出处
《中国妇产科临床杂志》
2012年第2期130-131,共2页
Chinese Journal of Clinical Obstetrics and Gynecology
基金
宁夏自然科学基金(NZ09143)
参考文献11
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