肾嗜酸细胞腺瘤6例诊治体会并文献复习

Diagnosis and treatment of renal oncocytoma of 6 cases and literature review

为提高肾嗜酸细胞腺瘤的诊断治疗水平,减少不必要的根治性肾切除术。本研究回顾分析2005年3月至2010年11月在中南大学湘雅二医院诊治的6例肾嗜酸细胞腺瘤的症状,实验室检查、影像学检查、病理学检查结果,以及手术方式,并对患者进行随访。6例患者无特殊症状,实验室检查未见明显异常,其中2例肾嗜酸细胞腺瘤在影像学上有相对特异性表现,手术前考虑肾嗜酸细胞腺瘤可能,行手术中快速冰冻切片检查,诊断为肾嗜酸细胞腺瘤,行肾脏部分切除术,余4例行根治性肾切除术,术后随访1~5年,6例患者均未见复发或转移。目前认为肾嗜酸细胞腺瘤是一种良性肾脏肿瘤,依据典型的影像学表现和术中快速冰冻切片检查,可诊断部分典型的肾嗜酸细胞腺瘤,治疗上行肾脏部分切除术或者是肿瘤剜除术,尽量减少根治性肾切除术。明确诊断需依据术后病理学检查结果,术后宜密切随访。

Toimprovethediagnosisandtreatmentofrenaloncocytomaandavoidunnecessaryradicalnephrectomy. The clinical data of 6 cases of renal oncocytoma diagnosed at the Second Xiangya Hospital Central South University from March 2005 to November 2010, including symptoms, laboratory tests, imaging, style of operation, pathological examination, and follow-up were retrospectively analyzed.There were no special symptoms and obvious abnormal laboratory tests in the patients. Two patients had relatively special imaging. Partial nephrectomy was performed in 2 cases of renal oncocytoma with typical imaging, while radical nephrectomy was performed on other patients because of misdiagnosis. No relapse and metastasis were found in the following 1 to 5 years.Renal oncocytoma is an uncommon benign tumor. Partial nephrectomy or tumor excision can be performed on patients diagnosed with renal oncocytoma according to typical imaging and intraoperative frozen section biopsy. The final diagnosis depends on pathological examination and regular follow-up is imperative for patients with renal oncocytoma.