失代偿期肝硬化患者医院感染相关因素临床分析

Related factors for nosocomial infections in cirrhosis patients during decompensated period

目的探讨引起失代偿期肝硬化患者医院感染相关因素。方法回顾性分析240例失代偿期肝硬化患者的临床资料,比较医院感染组及无医院感染组患者年龄、性别、肝功能分级、门静脉内径、肝硬化并发症、侵入性操作措施、应用抗菌药物、住院时间等差异。结果 240例患者发生医院感染60例,感染率25.00%,医院感染组患者年龄大、肝功能分级差、门静脉内径宽、肝硬化并发症多、侵入性操作措施比例高、预防应用抗菌药物多、住院时间长(P<0.05)等是医院感染的相关因素。结论引起失代偿期肝硬化医院感染危险因素较多,应从多个方面采取防措施。

OBJECTIVE To explore the related factors for nosocomial infections in patients with decompensated cirrhosis.METHODS The clinical data of 240 patients with decompensated cirrhosis were retrospectively analyzed.The differences in the age,sex,liver function classification,portal cirrhosis complications,the inner diameter,invasive operations,application of antibiotics,and the length of hospital stay between the infection group and non-infection group were compared.RESULTS Nosocomial infections occurred in 60 of 240 patients with the infection rate of 25.00%.Old age,poor liver function classification,broad inner diameter,multiple cirrhosis complications,high proportion of invasive operations,high frequency of prophylactic antibiotics use,and long hospital stay were the relevant factors for nosocomial infections.CONCLUSION Risk factors for nosocomial infections in patients with decompensated cirrhosis shall be prevented from various aspects.