急性脑卒中外周血WBC变化

Acute stroke in peripheral blood WBC change

目的:探讨急性脑卒中患者外周血白细胞数量的变化与病情及预后的关系。方法:应用sysmexXE-2100全自动血细胞分析仪检测430例临床诊断为急性脑卒中患者入院4h内外周血WBC总数,分组为WBC计数正常组(4-10×109/L)及WBC计数增高组(>10×109/L)。分别观察其预后评估:入院时、治疗后病程一周末、根据改良爱丁堡-斯堪的那维亚评分MESSS[1]量表评定神经功能缺损程度,BI量表评定日常生活能力。结果:入院4h及治疗一周末时,高WBC计数组MESSS评分明显高于正常组(P<0.05),BI评分明显低于正常组(P<0.05);治疗后2月正常组MESSS评分与WBC异常组比较差异有统计学意义。结论:脑卒中患者外周血白细胞计数与其病情及预后相关,可作为病情及预后的评估指标之一。

Purpose Discuss Acute stroke patient peripheral white blood cell volume changes with the severity and prognosis of relationship Method The application of sysmexXE - 2100 automatic blood cell analyzer 430 clinically diagnosed cases of acute stroke patients admitted to the 4h peripheral blood WBC number, Division for the WBC count in normal group （ 4 - 10×10^9/L ） and WBC count increased group （ 〉 10×10^9/L ）. Were observed to investigate the prognostic evaluation： at the time of admission, treatment after a weekend course, According to the modified Edinburgh - Scandinavia score MESSS Eli scale to assess the degree of neural func- tion defect, BI scale assessment of ability of daily life Result 4h after admission and treatment of a weekend, high WBC count group MESSS score was significantly higher than that in normal group （ P 〈 0. 05 ）, BI score was significantly lower than the normal group （ P 〈 0. 05） ; after the treatment of normal February group MESSS score and WBC abnormal group compare difference to have statistical significance. Conclusion： in patients with stroke and peripheral white blood cell count with the severity and prognosis related, can be used as evaluation index of severity and prognosis.