新型过氧乙酸溶液消毒消化内镜的效果评价

A new peracetic acid solution for disinfection of digestive endoscope

目的探讨新型过氧乙酸溶液应用于消化内镜消毒的临床价值。方法选择消化内镜40条分成两组，每组胃镜和肠镜各10条，观察组接受新型过氧乙酸溶液消毒10min，对照组接受常规2％戊二醛溶液消毒10min，比较两组消毒合格率，评价新型过氧乙酸溶液消毒的有效性。有效性获得证实后，再选择消化内镜80条分成四组，每组胃镜和肠镜各10条，分别接受新型过氧乙酸溶液消毒2rain、3min、4min和5min，比较消毒合格率，探讨新型过氧乙酸溶液消毒的高效性。结果对照组胃镜消毒合格率为100％（10／10），肠镜消毒合格率为90％（9／10），消毒后胃镜和肠镜均能检出菌落；观察组胃镜和肠镜消毒合格率均为100％，且消毒后胃镜和肠镜均不再检出菌落，明显优于对照组。新型过氧乙酸溶液消毒3min组、4min组和5min组胃镜消毒合格率均为100％（10／10），明显高于2min组的30％（3／10）（P〈0．05），但3min组仍可检出菌落；2min组肠镜消毒均不合格，4min组和5min组肠镜消毒合格率均为100％，明显高于3min的80％（8／10）（P〈0．05），但4min组仍可检出菌落。结论新型过氧乙酸溶液可用于临床消化内镜的消毒，较2％戊二醛溶液更符合消化内镜高水平消毒的要求。

Objective To evaluate the disinfective effect of a new peracetic acid solution for diges- tive endoscope. Methods Forty endoscopes were divided into experimental group and control group, 10 gas- troscopes and 10 enteroscopes in each group, the experimental group was disinfected with the new peracetic acid solution for 10 min, the control group was disinfected with 2% glutaral for 10 min, the disinfection effect was compared. Subsequently, 80 other endoscopes were divided into 4 groups, 10 gastroscopes and l0 enteroscopes in each group, each group was disinfected for 2 min, 3 rain, 4 min and 5 min, the disinfec- tion efficiency was evaluated. Results The disinfection rates of gastroscopes and enteroscopes in the control were 100% （10/10）and 90% （9/10）respectively. Bacteria were found in both endoscopes. In the experi- mental group, disinfection rates of both gastroseopes and enteroscopes were 100% （10/10）, and no bacteri- um was found, which was superior to the control, disinfection rates of gastroscopes of 3 min, 4 min and 5 min were all 100% （ 10/10）, which were higher than that of 2 min group （ 30% ） （ P 〈 O. 05 ）. Bacteria were found in 3 min group. Disinfection rates of 4 min and 5 min group were 100% （ 10/10）, which were higher than that of 3 min group （80%） （ P 〈 0. 05 ）. Bacteria were found in 4 min group, and 2 min group was not disinfected. Conclusion The new peraeetic acid solution is effective for clinic digestive endoscope disinfection, and is superior to 2% glutaral.