化学催化制备鱼油三甘酯

Preparation of Fish Oil Triglyceride by Chemical Catalysis

[目的]用化学催化方法制备鱼油三甘酯。[方法]采用酯交换反应,以鱼油乙酯和醋酸三甘酯为原料,制备三甘酯型鱼油,同时研究催化剂种类及用量(基于醋酸三甘酯的质量)、反应温度、物料比(油乙酯和醋酸三甘酯的摩尔比)、反应时间对鱼油三甘酯制备的影响,并通过液相色谱对鱼油三甘酯产物的成分进行定量分析。[结果]制备鱼油三甘酯的最佳条件为:催化剂为甲醇钠,用量为三甘酯质量的3.0%,反应温度为100℃,物料比为鱼油乙酯过量5%(相对于醋酸三甘酯),反应时间为2 h。在此最佳条件下制备产物三甘酯含量大于80%。[结论]通过此方法可实现鱼油乙酯向鱼油三甘酯的转化,成本较低,扩大了鱼油类产品在医药和保健品中的应用。

[ Objective ] The aim was to prepare fish oil triglyceride by the chemical catalysis method. [ Method ] Taking fish oil ethyl ester and glycerol triacetate as raw materials, prepare fish oil triglyceride by transesterification. Then to study the effects of the kind of catalyst and the amount of it （based on the mass of glycerol triacetate） , reaction temperature, mole ratio of fish oil ethyl ester to glycerol triacetate ,. reactiontime on the preparation of fish oil triglyceride. And the composition of the product was analyzed by liquid chromatography quantitatively. [ Resuit] The optimum conditions of the preparation of fish oil triglyceride were as follows： sodium methoxide was as a catalyst and the amount of it was 3.0% , reaction temperature was 100℃, mole ratio between glycerol triacetate and fish oil ethyl ester was 5% more of fish oil ethyl ester, reaction time was 2 h. Under these conditions, the content of fish oil trlglycerlde in the product was above 80%. [ Conclusion] This method can be achieved the conversion of fish oil ethyl ester to fish oil triglyceride, and has lower cost, can expand the application of fish oil products in the medicine and health products.