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全脑低灌注型血管性认知损害动物模型

Animal models of vascular cognitive impmnt of global cerebral hypoperfusion
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摘要 血管性认知损害（vascularcognitiveimpairment，VCI）是指由血管危险因素、明显或不明显的脑血管病引起的从轻度认知损害到痴呆的一大类临床综合征。寻找一种生理学可控且可复制的动物模型，对于VCI病理生理学过程的系统研究以及新型治疗方法的评价至关重要。 Vascular cogaitive impairment （VCI） refers to a large class of clinical syndromes caused by vascular risk factors, obvious or not obvious cerebrovascular diseases from mild cognitive impairment to demen- tia. Looking for a physiologically controllable and repeatable animal model is critical for the systematic research of the VCI pathophysiological processes and the evaluation of new treatment methods.
作者 孟楠 吕佩源
机构地区 河北省人民医院神经内三科
出处 《国际脑血管病杂志》 北大核心 2012年第2期156-160,共5页 International Journal of Cerebrovascular Diseases
基金 河北省自然科学基金（C2009001483） 国家留学人员科技活动择优资助项目（人力资源与社会保障部2009一ll_6）
关键词 认知障碍 脑缺血 疾病模型 动物 Cognition Disorders Brain Ischemia Disease Models, Animal
分类号 R749.1 [医药卫生—神经病学与精神病学]
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参考文献30

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国际脑血管病杂志
2012年 第2期

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