中医药治疗糖尿病肾病研究现状

Traditional Chinese Medicine Research Status of Diabetic Nephropathy

糖尿病肾病病变部位在脾肾,病机为本虚标实,本虚以肾阴虚、脾气虚为主,标实以血瘀为主,肾虚为病机根本,血瘀是病机特点,贯穿始终。正虚毒损肾络为本病核心,益肾解毒通络为治疗大法。分期分型辨证是符合本病发展规律的方案,中成药及中药注射液也各具特色。目前虽已制定辨证分型及疗效判定标准,临证仍多种多样,治法方药纷呈各异,临床报告可比性差,难以开展循证医学多中心协作。药物不良反应的报道涉及甚少,缺乏机理研究。早期治疗尚可逆转。应严格科研设计,加强对DN早期研究。

The diabetes nephrosis pathological changes in the spleen and kidney, pathogenesis for this empty mark true, the virtual to kidney Yin deficiency, spleen qi deficiency is given priority to, standard with real blood stasis primarily, kidney empty for basic pathogenesis, and blood stasis are pathogenesis characteris- tics, throughout. Are virtual poisonous damaged kidney disease for winding core, benefiting kidney detoxifica-tion treatment method for dredging. Staging points with the disease differentiation type is the development of the scheme, traditional Chinese medicine and traditional Chinese medicine injection and each has its own characteristics. At present although already make dialectical classification and curative effect decision criteria, the card still is varied, les formulas among the different, clinical report comparable poor, difficult to develo-ping the evidence - based medicine many centers cooperation. Reports of adverse drug reactions involving lit- tle, lack of its mechanism. Early treatment can reverse. Should be strict scientific research and design, to strengthen early DN.