COPD合并肺炎患者潮气末二氧化碳分压监测的临床价值

Clinical Value of End tidal PCO_2 Monitoring in COPD Patients Accompanied with Pneumonia

为探讨潮气末ＣＯ２ 分压（Ｐｅｔ ＣＯ２）监测的临床意义，对４５ 例慢性阻塞性肺疾病（ＣＯＰＤ） 并肺炎的患者Ｐｅｔ ＣＯ２ 与ＰａＣＯ２ 、ＰａＣＯ２Ｐｅｔ ＣＯ２（Ｐａｅｔ ＣＯ２） 与病情严重程度的关系进行比较。结果显示：轻症感染患者中，ＰｅｔＣＯ２ 和ＰａＣＯ２ 呈显著相关（ｒ＝ ０－８５２３ ，Ｐ＜ ０－０１） ；而１５ 例并发呼吸衰竭等重症感染患者，两者则无明显相关（ｒ＝０－３０６５，Ｐ＞ ０－０５） ；该１５ 例患者的Ｐａｅｔ ＣＯ２ 则明显高于轻症感染者（ Ｐ＜ ０－０１） ，表明动态观察ＣＯＰＤ 合并肺炎患者Ｐａｅｔ ＣＯ２ 的变化，对预测并发症发生和评估患者预后有一定的实用价值。

In order to investigate the clinical implication of end tidal CO 2 pressure (Pet CO 2) monitoring, the relationship between Pet CO 2 and PaCO 2, and Pa CO 2 Pet CO 2 (Pa et CO 2) and the disease severity was studied in 45 COPD patients accompanied with pneumonia. In the mild infectious patients, Pet CO 2 was significantly correlated with Pa CO 2 ( P <0 01). While in the 15 severe infectious patients associated with pulmonary failure, no correlation between them was found ( P >0 05). These 15 patients showed a significant increase of Pa et CO 2 as compared with that in the mild infectious patients ( P <0 01). The results indicated that the changes of Pa et CO 2 in COPD patients combined with pneumonia could predict the occurrence of complication and evaluate the prognosis of the patients.