室内环境因素和手足口病暴发的相关性研究

Study on the relationship between indoor environment and outbreaks of hand-foot-mouth disease

目的分析室内环境等因素和手足口病疫情暴发之间的关系,为科学改善环境状况减少手足口病疫情暴发提供科学依据。方法选取北京市2010年1～6月手足口病疫情暴发的32个班级为病例组,对照组为存在聚集性病例的19个班级和30个无病例班级,用病例对照研究方法研究室内环境危险因素与手足口病暴发的关系。结果单因素分析显示,疫情暴发班级、聚集性病例班级及无病例班级间窗地面积比(AC/AD)、室内紫外线照度和室内照度差异有统计学意义;线性回归结果显示,室内紫外线照度为手足口病暴发的保护因素,室内温度较高可能与手足口病暴发有一定关联。结论加强室内照度,特别是紫外线照度对预防手足口病暴发可能有一定作用。

Objective To explore the relationship between indoor environment and outbreaks of hand-foot-mouth disease（HFMD）,provide scientific basis for improving the environmental hygiene and decreasing the outbreak of HFMD.Methods Case-control study was conducted during January to June,2010 in Beijing to screen the indoor environmental risk factors.32 classes with outbreaks were included as case group,19 classes with sporadic cases and 30 classes with no HFMD were included as control groups.Results Statistical significant difference was found in AC/AD,indoor ultraviolet and indoor illumination among case group and two control groups.The standardized regression coefficient of ultraviolet as a protection factor was-0.254.However,the high indoor temperature was a risk factor.Conclusions Increasing the indoor illumination,especially sufficient ultraviolet illumination could prevent the outbreak of HFMD.