脊髓栓系综合征电生理检测特点及临床意义

Electrophysiological study of tethered cord syndrome

目的 利用电生理检测技术，评价脊髓栓系综合征（ＴＣＳ） 患儿神经功能改变。方法 对ＴＣＳ患儿组及对照组行胫后神经体感诱发电位（ＰＴＮ－ ＳＥＰ） 、胫后神经及腓总神经运动神经传导速度（ ＭＣＶ） 检测。结果 ＴＣＳ患儿组ＰＴＮ－ ＳＥＰ检测出现皮层电位潜伏期延长，波幅下降甚至消失，部分马尾电位波幅消失；ＭＣＶ 轻、中度减慢，动作电位波幅下降，甚至出现传导阻滞，病变随病情而加重。结论 ＳＥＰ、ＭＣＶ 检测对判断ＴＣＳ神经损害程度及部位，估计预后，具有重要意义。

Objective To evaluate the neurological function in patients of tethered cord syndrome with electrophysiological studies. Methods Patients with tethered cord syndrome underwent posterior tibial nerve somatosensory evoked potential study (PTN-SEP) and motor conductive velocity study of the posterior tibial and common peroneal nerves (MCV). The results were compared to those of the normal controls.Results In patients suffering from tethered cord syndrome, the cortical potential latency was delayed in PTN-SEP study. Its amplitude was low or disappeared. Slight to moderate decrease or complete block were detected in MCV. The active potential amplitude was decreased. MCV changes correlated with the clinical neurological changes.Conclusion PTN SEP and MCV may provide objective assessment of the neurological damage in tethered cord syndrome.