摘要
目的探讨弥散型和局限型脑干胶质瘤的病理学、超微结构特点以及增殖特性。方法收集18例脑干胶质瘤标本,应用苏木精-伊红染色观察18例脑干胶质瘤的形态变化,应用免疫组织化学方法检测10例脑干胶质瘤Ki-67蛋白表达,应用透射电子显微镜观察8例脑干胶质瘤细胞超微结构。结果苏木精-伊红染色结果显示：大多数弥散型脑干胶质瘤细胞生长活跃或具有恶性转化倾向。透射电子显微镜结果显示：弥散型脑干胶质瘤生长较局限型脑干胶质瘤活跃。免疫组化结果显示：所有肿瘤均表达Ki-67蛋白,弥散型脑干胶质瘤增殖指数明显高于局限型脑干胶质瘤（P〈0.01）。结论弥散型脑干胶质瘤较局限型脑干胶质瘤生长活跃、细胞增殖快,可能与其恶性生物学行为有关。
Using powder metallurgy technique, （Ti, W）C/Fe/Fe matrix surface composite was fabricated on 45 steel surface in-situ. The microstrueture of surface composite was investigated by XRD and SEM. The results show that the synthesized surface composite consists of （Ti, W）C particles and a-Fe as the binder phase. （Ti, W）C particles exhibit fine size and homogeneous distribution in the matrix. An excellent metallurgy-bond is observed between the surface composite and 45 steel.
出处
《热加工工艺》
CSCD
北大核心
2012年第6期76-78,共3页
Hot Working Technology
关键词
神经胶质瘤
脑干
病理学
超微结构
增殖
（Ti,W）C/Fe matrix surface composite
microstmcture
powder metallurgy
