摘要
目的探讨肉瘤样癌(SC)的治疗方法。方法结合1例SC患者的临床资料及文献复习,对本病的临床表现、诊断和治疗进行分析。结果 1例SC患者因逐渐加重的干咳、胸痛和呼吸困难3个月入院,经胸腔镜检查确诊。经吉非替尼治疗后症状消失,肿瘤稳定了4个月。SC是一种罕见的肺原发肿瘤,治疗方法包括手术、化疗和放疗,但是这些方法在晚期患者中常较难应用。报道1例Ⅳ期SC患者,经吉非替尼治疗后取得了较好疗效。结论晚期SC患者生存期短,生活质量差,吉非替尼可能为这类患者提供了可行的治疗方案。
Objective To investigate the effects of gefitinib in the treatment of sarcomatoid carcinoma.Methods Clinical data of a case of sarcomatoid carcinoma was analyzed and related literatures were reviewed.Results A patient with sarcomatoid carcinoma was admitted with progressive dry cough,chest pain and dyspnea for 3 months.The patient was diagnosed as lung sarcomatoid carcinoma by thoracoscopy and treated with gefitinib.After 2 weeks treatment,symptoms disappeared and tumor was stable for 4 months.Literatures review suggested that sarcomatoid carcinoma is a rare malignant tumor.Treatment of sarcomatoid carcinoma includes surgery,chemotherapy and radiotherapy,but these methods show little effect in advanced patients.In our case,the patient with sarcomatoid carcinoma in stage Ⅳ was treated by gefitinib and showed favourable effect.Conclusions Advanced sarcomatoid carcinoma patients have a short life span and poor life quality.Gefitinib may provide these patients a feasible therapeutic approach.
出处
《中国呼吸与危重监护杂志》
CAS
2012年第2期172-175,共4页
Chinese Journal of Respiratory and Critical Care Medicine
关键词
吉非替尼
肉瘤样癌
综述文献
Sarcomatoid carcinoma
Gefitinib
Literature review
