乳腺癌超声造影特征分析

Characteristics of breast neoplasms on contrast-enhanced ultrasonography and its clinical value

目的探讨乳腺癌超声造影特征及其临床价值。方法对常规超声不能确诊的225例乳腺肿块患者进行超声造影检查，观察造影后显像特征，并与病理结果相比较。结果乳腺恶性肿瘤的特征性表现多为病灶最大直径测值明显大于造影前（P〈0．05）．外形不规则，灶内造影剂分布不均匀，局部充盈缺损，局部造影剂滞留；血管走形扭曲，部分呈团块状，可见穿隔血管并呈快进快出。其中局部充盈缺损及造影剂廓清滞留的敏感度和特异度分别为89．0％和91．8％及93．4％和92．5％。结论超声造影对乳腺癌的诊断与鉴别诊断具有重要的临床价值。

Objective To investigate the characteristics of breast neoplasms on contrast-enhanced ultrasonography（CEUS） and its clinical value. Methods Two hundred and twenty-five patients with breast masses unable to be diagnosed by conventional ultrasonography were examined with CEUS. The characteristics of these masses on CEUS were analyzed and compared with the results of pathology examination. Results The typical features of breast cancers on CEUS were enlarged maximum diameter of the lesions on CEUS compared to pre-contrast （ P 〈0.05）, irregular shapes, heterogeneous distribution of contrast enhancement with perfusion defect or local retention of contrast signals, tortuous, massive or penetrating vessels rapidly entering and exporting from the lesions. The sensitivity and specificity of perfusion defect for breast cancer on CEUS were 89.0% and 91.8%, respectively; the sensitivity and specificity of local retention of contrast signals for breast cancer on CEUS were 93.4% and 92.5%, respectively. Conclusions It is valuable for CEUS in the diagnosis and differential diagnosis of breast neoplasms clinically.